The Role of the Intravenous IgA and IgM-Enriched Immunoglobulin Preparation in the Treatment of Sepsis and Septic Shock

Polyclonal Intravenous Immunoglobulins (IvIg) are often administered to critically ill patients more as an act of faith than on the basis relevant clinical studies. This particularly applies treatment sepsis and septic shock because current guidelines recommend against their use despite many investigations that have demonstrated beneficial effects in different subsets patients. The biology, mechanisms action, experience related administration IvIg reviewed, which aim give a in-depth understanding properties order clarify possible indications